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On the basis of limited data, patients with nonischemic cardiomyopathy with LV thrombus should be treated with OAC for at least 3–6 months, with discontinuation if LV ejection fraction improves to >35% (assuming resolution of the LV thrombus) or if major bleeding occurs. There are insufficient study data to determine whether OAC should be .Complete thrombus resolution was achieved in 62.3% (n=99) at a median of 103 days (interquartile range, 32–392 days). 17 Recurrence of thrombus or an increase in LV thrombus area was observed in 14.5% (n=23), a finding associated with poor adherence, prothrombotic conditions, and increased mortality. 17.
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